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Karl Landsteiner

Karl Landsteiner was an Austrian biologist and physician who made significant contributions to the field of immunology, particularly in the area of blood types. He is best known for his discovery of the blood groups A, B, AB, and O, which laid the foundation for modern blood transfusion techniques.

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He is best known for his discovery of the blood groups A, B, AB, and O, which laid the foundation for modern blood transfusion techniques. Born in 1868 in Vienna, Landsteiner initially studied medicine at the University of Vienna. He later pursued a career in research, focusing on immunology and bacteriology. In 1901, while working at the University of Vienna, Landsteiner made the groundbreaking discovery of blood groups. His experiments involved mixing blood samples from different individuals and observing the reactions between the blood cells. Through this research, Landsteiner identified the presence of different antigen markers on the surface of red blood cells that determine an individual's blood type. This discovery revolutionized the field of transfusion medicine, as it was now possible to determine compatible blood types for transfusion, thus significantly reducing the risk of adverse reactions. Landsteiner's work also led to the development of the ABO blood typing system, which is still widely used today. Furthermore, Landsteiner made other important contributions to immunology, including the identification of the Rh factor, a major antigen on red blood cells that can cause complications during pregnancy. He also conducted research on polio and meningitis, contributing to our understanding of these diseases. Landsteiner's groundbreaking discoveries earned him numerous accolades, including the Nobel Prize in Physiology or Medicine in 1930, which he shared with his colleague Erwin Popper. He continued his research and teaching career until his retirement in 1937. Karl Landsteiner's contributions to the field of immunology have had a lasting impact on medicine, particularly in the areas of blood transfusion and compatibility testing. His research and discoveries have saved countless lives and continue to be fundamental in modern medical practices.