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The vaccine is typically administered in three doses over a six-month period and provides long-term immunity against the virus. Hepatitis B is a highly infectious viral disease that affects the liver and can lead to serious complications such as liver cirrhosis and liver cancer. The vaccine is made from a part of the virus that does not cause the disease but triggers an immune response in the body, resulting in the production of antibodies that protect against future infections. The vaccine is recommended for all infants, as well as adolescents and adults who are at a higher risk of contracting the virus. This includes healthcare workers, individuals with multiple sexual partners, injection drug users, and people living in regions with a high prevalence of hepatitis B. The development and widespread use of the hepatitis B vaccine has led to a significant reduction in the number of new infections and related deaths worldwide. It is considered one of the most effective vaccines in preventing viral infections. Side effects of the vaccine are generally mild and include soreness at the injection site, fatigue, and low-grade fever. Serious allergic reactions are rare. The vaccine is not recommended for individuals who have had a severe allergic reaction to a previous dose or to any component of the vaccine. The Hepatitis B vaccine has been extensively studied and approved by regulatory authorities worldwide. It is included in routine immunization schedules in many countries and has made a significant impact on public health by reducing the burden of hepatitis B.