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Insulin analog

An insulin analog (also called an insulin analogue) is any of several types of medical insulin that are altered forms of the hormone insulin, different from any occurring in nature, but still available to the human body for performing the same action as human insulin in terms of controlling blood glucose levels in diabetes. Through genetic engineering of the underlying DNA, the amino acid sequence of insulin can be changed to alter its ADME (absorption, distribution, metabolism, and excretion) characteristics.

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DNA

DNA, also known as deoxyribonucleic acid, is a molecule that carries the genetic instructions used in the growth, development, functioning, and reproduction of all known living organisms and many viruses.

European Medicines Agency

The European Medicines Agency (EMA) is an agency of the European Union (EU) in charge of the evaluation and supervision of pharmaceutical products.

Insulin

Insulin is a hormone produced by the pancreas that plays a crucial role in regulating blood sugar (glucose) levels in the body.

Insulin-like growth factor

The insulin-like growth factors (IGFs) are proteins with high sequence similarity to insulin.

Insulin (medication)

As a medication, insulin is any pharmaceutical preparation of the protein hormone insulin that is used to treat high blood glucose.

Insulin glargine

Insulin glargine sold under the brand name Lantus among others is a long-acting modified form of medical insulin, used in the management of type I and type II diabetes.

Insulin receptor

The insulin receptor (IR) is a transmembrane receptor that is activated by insulin, IGF-I, IGF-II and belongs to the large class of receptor tyrosine kinase.