About

It is the most abundant class of antibodies, comprising about 75-80% of the total antibodies in the body. IgG plays a crucial role in the immune system by recognizing and binding to specific foreign substances, such as bacteria, viruses, and toxins. This binding process marks these substances for destruction by other immune cells, such as phagocytes and natural killer cells, or triggers other immune responses. There are four subclasses of IgG, known as IgG1, IgG2, IgG3, and IgG4, each with slightly different functions. IgG1 and IgG3 are effective at activating immune responses and are involved in the elimination of pathogens, whereas IgG2 and IgG4 have more regulatory functions, such as controlling inflammation. IgG antibodies are produced by B-lymphocytes, a type of white blood cell, in response to exposure to foreign substances. They can also be produced artificially and used as therapeutic agents to treat a variety of conditions, including immune deficiencies, autoimmune diseases, and certain cancers. The measurement of IgG levels in the blood is important in diagnosing and monitoring several medical conditions, such as infections, allergic reactions, and autoimmune disorders. Overall, IgG is a vital component of the immune system, providing protection against a wide range of pathogens and contributing to the body's defense mechanisms.