Etanercept
Etanercept is a biologic response modifier medication commonly used to treat autoimmune diseases such as rheumatoid arthritis, psoriasis, and ankylosing spondylitis. It is administered via injection and works by inhibiting the action of tumor necrosis factor (TNF), a protein involved in inflammation.
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It is administered via injection and works by inhibiting the action of tumor necrosis factor (TNF), a protein involved in inflammation. Etanercept is a fusion protein made up of two components: a soluble TNF receptor and a human immunoglobulin G1 Fc region. By binding to TNF and preventing it from signaling immune cells, etanercept helps reduce inflammation and alleviate symptoms associated with autoimmune diseases. This Wikipedia page provides detailed information about the pharmacology, clinical uses, adverse effects, and contraindications of etanercept, as well as its history, development, and regulatory approval. It also discusses the various biosimilar versions of etanercept that have been developed and provides references for further reading.